Ai for sure brother it's the most powerful hand gun
No.
That would be the .454 Casull, or the .500 Linebaugh currently.
The desert Eagle "only" fires .50 cal ammo, which in itself is lighter than forementioned. Add to that the fact that part of the bullet energy is used to reload (pistol vs revolver), and surely you'll understand that the Desert Eagle is not what you claim.
Also, I've fired both Desert Eagle and Casull and can confirm the theories above. You don't have to wear gloves to fire the DE...